Long-term effectiveness of oral vanadyl sulphate in streptozotocin-diabetic rats
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منابع مشابه
Effects of Vanadyl Sulphate on Glucose Homeostasis in Severe Diabetes Induced by Streptozotocin in Rats
Background: There is not any in vivo studies that shows inducing of euglycemia by vanadyl is independent from plasma insulin. Therefore in the present study we planned to investigate the antidiabetic effects of vanadyl in diabetic rats. Materials and Methods: Rats became severely diabetic by an IV injection of 50-55mg/kg streptozotocin (STZ), 15 days after the injection, the blood glucose of ...
متن کاملHISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY OF PANCREATIC ISLET BETA CELLS OF DIABETIC RATS TREATED WITH ORAL VANADYL SULPHATE
Vanadium salts have been suggested as a possible therapeutic agent for the treatment of diabetes. The aim of the present study was to clarify histological and immunohistochemical changes that occur in the pancreatic beta (β) cells of vanadyl sulphate (VS)-treated streptozotocin (STZ) induced diabetic rats. Male Wi star rats were made diabetic by injecting a single intravenous dose of STZ (...
متن کاملimmunohistochemical study of the pancreatic islet beta cells of diabetic rats treated with oral vanadyl sulphate
introduction: vanadium salts have been suggested as a possible therapeutic agent for the treatment of diabetes. the aim of the present study was to clarify immunohistochemical changes that occur in the pancreatic beta ([pancreatic islet beta]) cells of vanadyl sulphate (vs) treated stz induced diabetic rats. materials and methods: male wistar rats were made diabetic with injecting a single intr...
متن کاملEffects of Vanadyl Sulphate on Spermatogenesis in Male Rats
Background: It is known that vanadyl compounds are capable of alleviating hyperglycemia in streptozotocin induced diabetic rats. Objective: To examine the effect of vanadyl sulphate (VS) on spermatogenesis of male rats. Methods: Male rats (n=10) were administered 32 mg/kg/day of VS orally and 50 mEq/l NaCl (as drinking water) for one month. Meanwhile, 11 male rats, the control group, received ...
متن کاملEffects of Long-term Administration of Oral Sodium Nitrate on Liver Enzyme Concentrations in Type 2 Diabetic Male Rats
Introduction: Liver disorders in patients with type 2 diabetes (T2D) are mostly associated with higher serum levels of liver enzymes. This study aimed to investigate the effect of nitrate administration on the serum levels of alanine amino transferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) in rats with T2D. Materials and Methods: In this study, 24 male Wistar ra...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1993
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf00399953